This evokes Escobar's (2001) discussion, referring specifically to marginalized place-based social movements, of the need 'to create the networks on which manifold forms of the local can rely in their encounter with the multiple manifestations of the global' (p. 171).
This bears on how we understand dispositions (see the entry on dispositions) because the triggering conditions are often complex and multiply realized (including manifestations without a trigger), as well as the fact that cells exhibit dispositions with multiple possible manifestations (cell types) in specific sequential orderings (Hüttemann and Kaiser forthcoming).
Among the most common manifestations are the renal and immune system involvement; the first one is responsible for the majority of the morbidity and mortality of patients, and the second strongly associated with multiple clinical manifestations.
More survivable cases, occurring with lower infusion rates, have replaced lethal PRIS with multiple clinical manifestations.
Up to 30% of Crohn's patients may present with multiple extraintestinal manifestations with the occurrence of one increasing the chances of others [ 1].
Rheumatoid arthritis (RA) is a disease with multiple clinical manifestations and chronic complications that requires a multidisciplinary team to treat and monitor patients.
Altogether, it seems that circadian disruption is associated with multiple negative manifestations, whereas resetting of circadian rhythms could lead to increased longevity.
In Fig. 5, control patients are subjects with multiple autoimmune manifestations (which include enteropathy, endocrinopathies, and skin diseases) (n=5) who were investigated for the presence of mutations in FOXP3, but were found to be negative.
In most cases, renal vascular damage is but one of the multiple manifestations of multisystem vasculitis, a rare life-threatening complication associated with sarcoidosis.
