These assumptions mimic a diagnostic test with relatively low sensitivity, high specificity and a disease with moderate prevalence.
Due to that reason, Poland can be placed among the European countries with moderate prevalence rates [ 17, 32, 33].
Fifteen trials were conducted in populations where worms were of high prevalence or intensity (community category 1), 12 in populations with moderate prevalence and low intensity (category 2), and 10 in populations with low prevalence and low intensity (category 3).
The highest risk of abortions (> 1.3%) and increased insemination index (number of inseminations per pregnancy) (> 1.9) occurred in herds with a moderate prevalence of BHV-1 antibodies (1-491-49% cows.
The survey was conducted at medical residency training programs in Baltimore, MD, and Philadelphia, PA, cities with a moderate prevalence of tuberculosis; the case rates per 100,000 population were 4.5 and 4.2 for Baltimore and Philadelphia, respectively, in 2004 [ 32].
Even with a moderate prevalence, there may be a large reservoir of HCV and HBV-infected persons in Morocco, which indicates that many people are at risk of developing chronic liver disease related to viral hepatitis, added to the fact that antiviral therapy is not affordable by the vast majority of people in developing countries.
In the present study, NPV of POCT was assessed in a tertiary level Centre in a population with high and moderate prevalence of CD, such as that represented by patients referred with the suspicion of CD and first degree relatives, respectively.
The required sample size of at least 300 men and 300 women in every site allowed more sites the opportunity to participate in the study and provided adequate power for estimating COPD prevalence, but it limits our ability to draw conclusions regarding potential risk factors with low to moderate prevalence, particularly in our never-smoker population.
A large series of patients has been obtained with indisputable diagnoses and, besides lung diseases already associated with NSP [ 4], we further show that some conditions as interstitial pneumonia, pulmonary hypertension or bilateral lung transplantation are associated with low to moderate prevalence of the syndrome.
Interestingly, in previous studies, anti-cN-1A autoantibodies were also found at a moderate prevalence in patients with Sjögren's syndrome (23 36%) and systemic lupus erythematosus (14 20%) [38, 39].
The sample was representative of a 65-year-old diabetic population with mildly uncontrolled disease and a moderate prevalence of complications.
