Sentence examples for with minimized side effects from inspiring English sources

A basic understanding of disease mechanisms is a prerequisite for finding effective therapy with minimized side effects.

Because NPs have the affinity to acidic environment, which characterized tumor tissue, it is believed that selective targeting strategies with NPs facilitate more effective cancer detection and treatment with minimized side effects to normal cells [1].

Thus, the challenge is to design safe, approvable, and easily scaled-up nanocarriers that simultaneously meet the two pairs of requirements of 'drug retention in circulation versus intracellular release' and 'stealthy in circulation versus sticky (cell-binding) in tumor' at the right places in order to deliver a cytosolic drug dose lethal to cancer cells with minimized side effects.

Still researching is going on to find out the more effective herbal drug to cure the diabetes and reduced the free radical formation with minimized side effect.

Mechanistic understanding of the interaction between cavitation events and cells and tissues, as well as the subsequent cellular and molecular responses will lead to new design strategies with improved efficacy and minimized side effects.

The choice of the optimal mesh for a particular indication with the highest functionality (hold shape) as well as minimized side effects remains difficult.

Our novel strategy would have profound implications in both enhanced chemotherapy efficacy and minimized side effects.

In this study, we developed pH and redox-responsive crosslinked polypeptide-based combination micelles for enhanced chemotherapeutic efficacy and minimized side effects.

When carbon/hydrogen isotope is used to selectively engineer some properties (e.g., thermal transport and kinetic stability), such isotopic independence of the Invar and Elinvar properties can guarantee the minimized side effects on structure and stiffness.

Thus, the maximized drug activity and the minimized side effects like toxicity and antigenicity should be considered for utilization of miRNAs in breast cancer therapy.

Taken together, these systematic observations offer strong support for the hypothesis that natural selection for maximized metabolic benefits and minimized side effects of the uncontrolled PAH intermediates has restricted the evolutionary trajectories of mycobacterial PAH metabolism.