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Results from the antagonist studies showed that CP-154,526 and NBI 27914 either fully or partially reversed the referred ulcer pain with minimal effective doses (MED) equal to 3 and 10 mg/kg, respectively.
Given the striking pattern of similar and rapid effects across four common and widespread species, including a volant bird, intense urbanization may represent the most severe form of fragmentation, with minimal effective movement through the urban matrix.
Pregabalin was active on carrageenan-induced mechanical hyperalgesia with minimal effective doses of 3 mg/kg and 6 mg/kg [ 23, 24].
However, if you must fire, fire two reflexive shots to the chest with minimal effective aiming followed by a single shot to the head with careful aiming.
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A reduction of effective dose up to 70% has been achieved with minimal effects on lung quantitative results.
A reduction of effective dose up to 70% can be achieved with minimal effects on lung quantitative results.
The effective dose can be reduced by up to 70% with minimal effects on quantitative results.
We transfected HeLa cells with BRCA1 or siCtrl, and treated with a minimal effective dose of bortezomib (10 nM) for 20 h before cells were processed for cell cycle analysis by the fluorescence-assisted flow cytometry.
In GAD long term therapy, SSRI (paroxetine) could represent a valid alternative to BZD if starting with a minimal effective dosage.
Optimisation led to the identification of the brain penetrant, orally bioavailable Y5 antagonist 9b which significantly inhibited the food intake induced by a Y5 selective agonist with a minimal effective dose of 30 mg/kg po.
Gabapentin reversed carrageenan-induced hyperalgesia with a minimal effective dose of 10 mg/kg for mechanical hyperalgesia [ 23, 24].
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