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The phrase 'with minimal effect' is correct and can be used in written English.
It is typically used to describe something that had a small effect on something else. For example: "The government's attempts to reduce global warming have had minimal effect on rising temperatures."
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The demanding task is to find a combination that is maximally effective on cancer cells with minimal effect on non-cancer cells.
A State Department program to counter the caliphate's messaging has cycled through a series of initiatives with minimal effect.
CO emission was substantially reduced with hydrogen enrichment, with minimal effect on NO emission under premixed combustion.
Colon said the procedure was not 100% effective, but if allowed to proceed to full measure, it would "reduce the mosquito population below disease transmission levels with minimal effect on the environment".
Some say restoring high-end tax rates to levels similar to those in the Clinton administration will help trim the deficit with minimal effect on the economy.
This improves component reuse there and improves the ability to change a layer's implementations with minimal effect on the other layers.
Applications of the algorithm on arm reaching experimental data obtained with blocked and event-related designs demonstrate attenuation of motion artifacts with minimal effect on the brain activations.
Resilience is the ability of a system or organization to react to and recover from disturbances with minimal effect on its dynamic stability.
The understanding of the pathophysiology of a large number of cancer types provides a strategy to target cancer cells with minimal effect on normal cells.
The lessons learned may benefit laboratories with a similar interest in making the transition to a digital imaging laboratory with minimal effect on patient scheduling and staff satisfaction.
Results from this experiment demonstrated that OPT, when fed to heifers, increased ADG, calculated carcass ADG, and HCW with minimal effect on carcass quality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com