Sentence examples for with lesser effects from inspiring English sources

It acts on opioid receptors in the intestinal wall with lesser effects on muscarinic receptors to inhibit peristalsis; it may also have an inhibitory effect on secretions.

An increased understanding of tumor biology and the radiation response has led to the nomination of several pathways whose targeted inhibition has the potential to radiosensitize tumor cells with lesser effects on normal tissues.

Recently, Narazaki et al. [53] showed in a model in which transferred T cells are used to prevent tumor recurrence in a rechallenge model, that for agonistic anti-4-1BB therapy, 4-1BB was more important on the transferred T cells with lesser effects on host cells.

In contrast, GW0742 reduced BMP2 and BMP4 mRNA levels in OPCs, with lesser effects in astrocytes.

This was notable over the age of 40, with lesser effects below that age, except for a relative reduction of 50% for women aged 20 24.

This suggests that structural effects of PHD inhibitors will be most prominent in the context of neovascularization, with lesser effects on cells in intact vessels.

Hence, multiscale techniques which have the capability of representing the feature in one or more resolution with lesser effect of these recording conditions have been used since 1990s.

Addition of age to these models markedly improved the RMSE of parametric models (mean reductions in RMSE of 0.28 m3 ha−1 year−1) with lesser effect on non-parametric models (mean reductions in RMSE of 0.03 m3 ha−1 year−1).

In determining the appropriate treatment option, the patient has a distinct dilemma if a minimal invasive treatment with lesser effect than hysterectomy should be chosen or if a hysterectomy should be chosen which is a major surgery and requires longer recovery than the minimal invasive alternative.

Tetra Pak® sheets with an upward-facing (acting as reflective insulation) or downward-facing (functioning as radiant barrier) aluminized side or with double-sided aluminum coating showed a reduction in the roof's inner surface temperature, comparable to commercial insulating sheets, though with lesser effect on indoor temperatures.

Moreover, mutation of Ser649 and Ser650 results in loss of lipolytic activity, with lesser effect on non-lipolytic activity.