This is not to say that research in children is not without limitations; with less prevalence of childhood disease [ 15] and smaller amounts of therapeutic agents designed for use in children [ 16], enrollment remains a challenge.
Though low-glycemic-response diets are associated with less prevalence of type 2 diabetes, cohort studies have not consistently found a relation between dietary glycemic index or load and risk of diabetes (21, 22); furthermore, whether the glycemic response causes diabetes is not established.
Although Bangladesh is still considered as a low prevalence country for HIV/AIDS with less than 1% prevalence rate, it is estimated that 6.4% of drugs users are infected by HIV/AIDS in the capital city.
Colombian-born Fernando Botero is perhaps Latin America's greatest living visual artist.But nowadays Colombia has become associated with less attractive features: the prevalence of illegal drugs, and the violent disorder of its guerrillas and paramilitary bands.
However, extrapolation of the meta-analysis results to asymptomatic screening populations with less than 20% disease prevalence might produce such selection bias.
Compared to patients whose CKD stage remained 3a, those who were reclassified to stage 2 range eGFR using the CKD-EPI equation were younger, more were female, with less microalbuminuria, a comparable prevalence of macroalbuminuria, fewer comorbidities and were prescribed fewer antihypertensive and lipid-lowering drugs (table 3).
Although a meta-analysis of observational studies of circumcision in MSM populations by Millet et al. could not detect a consistent protective effect, the authors did find a non-significant reduction in odds in settings with less than 50% circumcision prevalence, and concluded that more data on MSM who engage primarily in IAI would be helpful [ 24].
WHO suggested a selective helminth treatment for area with less than 20%% of helminth prevalence, a yearly single dose Albendazole treatment when the prevalence is 20-50 % and biannually when it is above 50%%, which could be done through schools [ 1, 11].
Importation pressures followed trends in related hospital prevalence densities, with less consistent and sizeable associations with community or ICU trends.
Children infected by vertical route (mother to child) may have greater tolerance to HBV with less hepatic damage, but greater prevalence of the chronic stage [ 16].
High prevalence areas are those where sickle cell disease is estimated to affect more than 1.5 per 10,000 pregnancies and low prevalence those with less than 1.5 per 10,000.
