Sentence examples for with large prospective from inspiring English sources

A difficulty in this respect, however, was that the meta-analysis of randomized controlled trials on LH versus AH [3] reported a much higher complication rate as compared with large prospective [4, 13] and retrospective case series [5, 14, 15].

These findings need to be confirmed with large prospective studies and a formal pharmacokinetic-pharmacodynamic analysis.

In the near future, further studies must meet several challenges: first, studies with large prospective cohorts with well phenotyped patients are needed.

In the setting of HIV few data are available and the effects of vitamin D 3) supplementation on insulin sensitivity need to be evaluated with large, prospective studies.

Similar to the WS, this question can only be addressed with large prospective global studies, which are under way (IDAMS study above).

Future directions include more rigorous analysis of risk factors for VAI and confirmation of these data with large prospective, observational studies.

Although this remains speculative, such questions could be addressed with larger prospective studies.

This is an exploratory study and needs confirmation with larger, prospective studies.

Whether or not PET/CT can make an impact on deciding the management of patients with recurrent HPCs as described in our case remains to be seen and certainly merits validation with larger prospective studies.

Future developments such as 3D images of the entire surgical field and automated intraoperative depths measurements, together with larger prospective trials, will have to evaluate how much this technology can improve outcome measures in big-bubble DALK surgery.

Our findings are in contrast with several large prospective studies that have shown that QUS of the calcaneus can predict fracture risk nearly as good as DXA [ 12- 14].