Sentence examples for with large effects from inspiring English sources

As such, GWAS has largely not succeeded in identifying disease genes with large effects, raising the concept of the "missing heritability" of common disease (Manolio et al. 2009).

The traits were largely controlled by a limited number of genomic regions with large effects.

All the same, beneficial mutations with large effects do appear, just much, much less frequently.

For instance: is it the case that most beneficial mutations have small effects — and how often do beneficial mutations with large effects happen?

So far, the examples presented are all major genes with large effects.

Two segments with large effects have been positionally cloned, allowing the identification of two major genes.

On the other hand, only QTLs with large effects on agronomic traits can pass their effects from parents to hybrids.

The mapping population sizes were generally relatively small (between 100 and 150 accessions), enabling the identification of several QTLs with large effects but offering little resolution.

For example, it is possible to override the liability scale established by small effects of a number of genes with large effects on the disease phenotype [24, 71].

The excellent fit with large effects and negligible error proves the triple dissociation.

Sequence variants with large effects, however, may also contribute to variation in complex traits, such as circulating lipid levels.