These chimeric molecules act as decoys by binding to and sequestering RANKL, thus preventing it from interacting with its native receptor on hematopoietic osteoclast precursors and mature osteoclasts.
Note that although a similar chimera has been expressed in the yeast S. cerevisiae [ 28], it was expressed with its native signal peptide, and its specific activity was not reported.
Secondly, Ant 4 significantly reduced the uptake of putrescine, demonstrating that this conjugate not only used the PTS, but that it could also successfully compete with its native polyamine for uptake.
Facebook's making a killing with its native, in-feed, auto-play video ads, and now it's going to let other developers earn money off them too.
The new bluebird trail with its native grasses attracted them, she said.
The exchange spoke volumes about the Pakistani diaspora's evolving engagement with its native country.
In other words, America's shameful history with its native inhabitants is echoing across these riverbanks this late summer.
To do this, we introduced selD with its native promoter on a multi-copy plasmid, C. difficile KNM6 pKNM62.
TiN, in contrast, leads to much less controllable processes and only when coated with its native oxide, or with thick catalyst films, yields large diameter nanotube forests.
In this study, the reaction of MCR from Methanothermobacter marburgensis
Jam, M. et al. Unraveling the multivalent binding of a marine family 6 carbohydrate-binding module with its native laminarin ligand.
