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Abundance generally declined with increasing modification, but was quite variable.
Initiator concentrations were optimized and the crosslink densities shown to increase with increasing modification.
MDA-MB-231 cells incubated with aHNE and subject to click chemistry revealed a concentration-dependent increase in aHNE adduction of Pin1, with increasing modification observed as low as 2.5 μM.
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Since upregulation of DPAGT1 expression in OSCC is associated with increased modification of glycoproteins with complex N-glycans (Liu et al. 2013), it is likely that in the absence of mutations these structures are responsible for the observed increased activities of EGFR and FGFR in oral cancer.
Human specimens of OSCC display induced expression of DPAGT1 and GPT protein levels, which is associated with increased modification of E-cadherin and collagen triple helix repeat containing 1 (CTHRC1) with complex N-glycans (Nita-Lazar et al. 2009; Liu et al. 2013).
The blood pressure in the intervention group was improved over the usual care group and this improvement was associated with increased modifications of treatment regimens.
Moreover, MGO was also shown to modify the co-repressor mSin3A, which results in increased recruitment of O-GlcNAc-transferase, with consequent increased modification of the transcription factor Sp3 by O-linked N-acetylglucosamine [46].
Conversely, induced DPAGT1 expression in MDCK cells leads to increased modification of E-cadherin with complex N-glycans and its reduced membrane association (Sengupta et al. 2010, 2013).
We found very similar patterns of declining species richness with increasing habitat modification between taxon-specific groups of similar geographic range categories.
Contact angle decreased with increasing time of modification.
The evolution of higher order harmonics were observed in association with increasing micro-structural modification.
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