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Many of these chemicals are highly toxic to cyanobacteria, thus strains with increased tolerance need to be developed.
Our success with increased tolerance towards crude glycerol and increased butanol productivity by EMS mutagenesis confirmed the efficiency of EMS for development of C. pasteurianum mutants.
However, there was no evidence of acclimation to contaminated diets, nor a cost of reduced feeding for those genotypes with increased tolerance.
Z. mobilis strains with increased tolerance toward furfural and acetic acid have been obtained by sequential transfers of cell cultures to synthetic media containing increasing concentrations of inhibitors (Shui et al. 2015).
This evolution of an Escherichia coli MG1655 derivative at neutral pH in minimal media produced a strain with increased tolerance not only to octanoic acid, but also to hexanoic acid, decanoic acid, n-butanol and isobutanol.
The intraspecific differences in sensitivity identified among the wheat varieties imply the options for selecting varieties with increased tolerance to UV-B/UV-A radiations to future attempts in plant breeding.
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Less aggressive ventilation with increasing tolerance of still-acceptable levels of hypercapnia and hypoxaemia.
We also found evidence that temperature-mortality relationships have changed over the period from 1973 to 2006 (see Fig. 3), with increasing tolerance to the hottest temperatures.
Further work has shown alteration in the basal sensitivity of these Mc1re mutant mice, with an increased tolerance to thermal (heat) stimuli and in the tail clip and abdominal constriction tests [20] with no sex specific difference noted.
This suggests that therapeutically targeting both arms of the protein degradation pathways may be of benefit in diseases such as RA that are associated with an increased tolerance to ER stress.
These marijuana users do not meet the clinical definition of addiction, which includes an inability to stop using the drug, an uncontrollable obsession with it and increased tolerance.
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