Exact(1)
Disc degeneration usually is associated with increased breakdown of matrix, decreased synthesis of aggrecan and collagen, cell loss through apoptosis, and cluster formation by surviving cells [ 4- 7].
Similar(59)
Cachexia is frequently associated with inflammation, insulin resistance, anorexia and increased breakdown of muscle proteins [ 23, 24].
This was supported by modest associations with increased tryptophan breakdown and lower neuroprotection ratio-B (β -0.3/-0.28, p = 0.02/0.03).
In a large prospective study of trauma patients, with serial blood sampling, Oshiro and colleagues have reaffirmed the presence of an early coagulopathy of trauma and have shown it to be defined predominantly by a fibrinolytic phenotype with increased fibrinogen breakdown [ 1].
Cartilage degeneration is associated with an increasing loss of mechanical resistance which results an increasing breakdown of the chondral layers (grade 2 lesions).
Infection, inflammation, and injury induce a catabolic state, with increased endogenous protein breakdown and impaired anabolism.
Porphyromonas gingivalis is a Gram-negative pathogenic bacterium associated with increased risk of periodontal breakdown and disease recurrence [ 3].
With increased migration and family breakdowns Vietnamese children are at greater risk of abuse, exploitation, violence and neglect.
We noted alterations in the expression of genes encoding enzymes that control fat synthesis and breakdown, consistent with increased SNS activity.
The pathologic induction of ECM breakdown is associated with increased tropoelastin production and the scattered deposition of misassembled elastic fibres in the lung [18].
Chemotherapy cytotoxic effects vary in severity according to therapy schemes and patient susceptibility, many of them may lead to intestinal mucosal damage, heavy inflammatory responses, often associated with increased epithelial cell death, intestinal epithelial breakdown, and luminal bacterial translocation [ 2, 3].
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