Sentence examples for with improved benefit from inspiring English sources

Theoretically, increased experience with a specific drug would improve patient selection, and therefore is associated with improved benefit, decreased harm and decreased risk of discontinuation in these patients.

With improved benefits emerging as a key battleground before May's Holyrood elections, Neil told MSPs the new agency would have a duty to "command the confidence of users by being cost effective and well-managed".

Furthermore, in light of the findings from several studies suggesting that 5-FU negatively affects outcome for microsatellite unstable tumours (Barratt et al, 2002; Ribic et al, 2003; Kim et al, 2007), the herein observed association between SATB2 expression and MSI status fits with the improved benefit from adjuvant treatment seen for patients with SATB2 high tumours.

In addition, the evaluations of psychomotor or memory function at zaleplon peak plasma concentrations show much less impairment than noted with other hypnotics, suggesting an improved benefit:harm profile for zaleplon compared with older agents.

Lung cancer treatment has recently moved toward a customized approach based on the molecular characteristics of tumors: patients with EGFR mutations may show improved benefit from EGFR tyrosine kinase inhibitors (TKIs; e.g., erlotinib and gefitinib), and those with ALK translocations from ALK inhibitors (e.g., crizotinib).

In recent years, the dilemma between transfection efficacy and adverse PEI activities has been addressed from in-depth investigations of cellular processes during transfection and elucidation of molecular mechanisms of PEI-mediated toxicity and translation of these integrated events to chemical engineering of novel PEI derivatives with an improved benefit-to-risk ratio.

Continued research to understand the molecular mechanisms of lipid droplet formation and subsequent steatosis could help in the development of novel therapeutic treatments with improved risk:benefit ratios.

Thus, the analysis of hepatotoxicity and steatosis in relation to VPA treatment, and the development of model systems for this research, are important priorities because they will enable the development of novel therapeutics with improved risk:benefit ratios.

This information may be useful for rationally designing functional foods with improved nutritional benefits.

Cultivars with high levels of phenolic compounds, antioxidant capacities, and α-glucosidase inhibitory activities could be selected for use in blueberry breeding programs to develop new lines with improved health benefits.

We found that, in addition to improved environmental outcomes, system planning could consistently identify development options with improved economic benefits for sectors such as navigation, water supply, flood management, and agriculture, compared to status quo planning and management.