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In fact, increased MMP-9 levels have been reported to be closely associated with high stages of cancer in various human tissues, including UC-UUT [ 16, 18].
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Thrust force, torque and work piece stress distributions are estimated to decrease by the use of step drill with high stage ratio.
High expression was also significantly correlated with high stage and grade.
Hence, we may have underestimated the weight of patients presenting with high stage cancers.
The relative risk was increased for patients with high stage disease.
We found that the expression of the CT genes was highly associated with high stage and grade of the disease.
In contrast, AGR2 was a strong predictor of tumor recurrence for individuals with high stage prostate cancer.
Importantly, this correlated to an approximately four-fold increased risk of disease recurrence and death in patients with high stage, high-grade serous carcinoma.
We found that a relatively higher expression of AGR2 in patients with high stage prostate cancer stratified these individuals as less likely to have a tumor recurrence.
Thus, either loss of bcl-2 expression or gain of abnormal p53 expression is associated with high stage and poor prognosis.
Additionally, Liu et al. showed c-MET mRNA and protein overexpression in primary CRC with high stage and positive nodal metastasis [ 20].
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