Mostly of them were up-regulated with highest induction of 22-fold for one member (AW705829).
WRKY18 was induced up to two fold at 24 hai with highest induction of 14 fold at 72 hai.
22 Similarly, LOX3 (lipoxygenase 3) is another highly connected node of the immune network with higher induction upon cytokinin treatment (Fig. 2D).
IRF-1 is also stimulated by rIL-1β but to a much reduced level, and interestingly it had the same expression profile as when stimulated with IFN-γ with highest induction at 24 h.
Among the genes with highest induction level are the subunits of the DMSO reductase, which is an alternative terminal oxidase under anaerobic conditions, and three subunits of an ABC transporter (sugar/glycerolphosphate-specific).
Real-time PCR analysis generally confirmed either induction or suppression in multiple tumor samples but with higher induction ratios; e.g. from Fig. 5, the level of ANGPTL4 was measured by PCR as induced 19 to 453 fold with a average fold induction of 185 SD = 170 for 10 tumors (2 of each type).
For example, in the MmBMM dataset, we found an NF-κB signature in 659 genes, of which 55 also contained an ISRE element; among the 65 NF-κB targets with highest induction by LPS, 12 genes also had an ISRE element.
Gene expression of cbfa-1, ALP, α1 chain of type I collagen, and osteocalcin were upregulated in fetal bone cells after 12 days of treatment, with higher inductions than for adult and mesenchymal stem cells.
The metal induction of these seven genes (czcJ, mmrQ, copQ, mmmQ, mmtQ, and mmsQ/Q1) follows a varied and overlapping response, with very high induction by some metals and no induction by other metals.
