When grouped according to severity of disease using the Bethesda classification, there were 72 with low grade lesions (LGSIL) and 164 with high grade lesions (HGSIL).
The majority of patients presented with high grade neoplasms (grade 3: 47.8% grade 2: 43.5% grade 1: 8.7%).
This is a four-grade scale with higher grade indicating more severity [ 28].
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Postoperative complications in the first 90 days were recorded and assessed by the Clavien-Dindo classification at grades ranging from one to five, with higher grades indicating greater severity [ 19].
Also, high levels of Gal-1 were associated with high-grade tumors (grades III/IV) when compared with low-grade (grade I or grade II) tumors (P<0.001).
SOCS7 expression decreased with higher tumour grade (Grade 3 vs. Grade 2 p = 0.037).
Even in those OA patients with higher OA severity (K/L grade IV), the serum levels of this antioxidant enzyme appeared more significantly increased than in OA patients with lower K/L grade (p < 0.001).
Low grade was compared with moderate and high grade.
Prognostic stratification scales do not seem to be reliable predictors of mortality; however, high PESI grades correlates with high severity illness.
