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Adsorption and displacement results agreed, indicating relatively high MW SRHA constituents bound with greatest affinity.
There is a tendency for those polymers with greatest affinity for C60 to have the same types of functional groups as the better solvents.
Finally, unlike intact VAR2CSA, both DBL3X and DBL6ɛ bind to various carbohydrates, with greatest affinity for ligands with high sulfation and negative charge.
Thus, OM719 represented the group with greatest affinity towards the moAb G12, OH727 those of intermediate reactivity and OF720 those not recognised by this antibody.
Globally, the biological role of CRP after binding to ligands is to trigger the complement pathway [ 7] CRP binds with greatest affinity to phosphocholine residues, and with less affinity to native and modified lipoproteins [ 44], damaged cell membranes, a number of phospholipids, small nuclear ribonucleoprotein particles, and apoptotic cells [ 45].
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The drug binds with great affinity to the bacterial enzyme dihydrofolate reductase (DHFR) [21].
Unlinked ZIKV protease is more active and binds substrate with greater affinity than linked ZIKV protease.
From our screen, several novel ligands that persistently bind to the M1 receptor with greater affinity than xanomeline were discovered.
We present here three new variants of Nelfinavir, which we have designed with computational tools, with greater affinity for HIV-1 Protease than Nelfinavir itself.
Dissociation constants obtained using both techniques revealed that some of the newly isolated chimeras bind 2F5 with greater affinity than previously identified chimeric rhinoviruses.
We report here a series of catechol compounds with great affinity for the PLAP isozyme and significant selectivity over other members of the AP superfamily.
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CEO of Professional Science Editing for Scientists @ prosciediting.com