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The drug binds with great affinity to the bacterial enzyme dihydrofolate reductase (DHFR) [21].
We report here a series of catechol compounds with great affinity for the PLAP isozyme and significant selectivity over other members of the AP superfamily.
The N-terminal RNA-binding domain (RBD1) of the human U1A protein is evolutionarily designed to bind its RNA targets with great affinity and specificity.
Highly sensitive and selective nanosensor for labile iron pool (LIP) determination, has been designed and prepared by immobilization of Fluoresceine Desferrioxamine (Fl DFO), a bifunctional fluoro-siderophore probe molecule with great affinity for iron ions (pKf = 30.7), into highly ordered mesoporous silica structure.
2A, 2B) When analyzing vasoactive areas, note that macroscopic vasodilatation corresponded to microscopic chromophilic areas with great affinity to Hematoxylin - Eosin stain, where the tumor is fully active with large number of cell mitosis and pleomorphism.
Whereas EVTs bound with great affinity to all α integrin subunits (Figure 6B), LacZ-expressing JEG-3 cells failed to bind to α1, α4, and αv antibodies (Figure 6B).
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Unlinked ZIKV protease is more active and binds substrate with greater affinity than linked ZIKV protease.
Adsorption and displacement results agreed, indicating relatively high MW SRHA constituents bound with greatest affinity.
From our screen, several novel ligands that persistently bind to the M1 receptor with greater affinity than xanomeline were discovered.
There is a tendency for those polymers with greatest affinity for C60 to have the same types of functional groups as the better solvents.
Finally, unlike intact VAR2CSA, both DBL3X and DBL6ɛ bind to various carbohydrates, with greatest affinity for ligands with high sulfation and negative charge.
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CEO of Professional Science Editing for Scientists @ prosciediting.com