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Emphysematous changes can occur with further progression to parenchymal necrosis.
Within 15 min after the injection, rats first showed deep breathing and increased salivation followed by scratching with further progression to rearing and generalized tonic/clonic seizures within 50 60 min, which lasted for 2 3 h.
With further progression, miniaturization continues and the muscle loses attachment to the secondary follicles in affected FUs completely.
Additional genetic and epigenetic events are associated with further progression through increasingly severe degrees of dysplasia to adenocarcinoma.
In proliferative lupus nephritis, however, a high activity index with more than 50% of glomerular crescents is a risk factor associated with further progression of nephritis [ 5].
With further progression degenerative changes were noticed in the remaining hamstring muscles and to a lesser degree in the vastus lateralis and vastus intermedius muscles.
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All the patients, but one (Case 6°), showed a marked improvement in HHS, with no further progression of the disease at the MRI analysis (Table 4).
After an average follow-up period of 15.43 ± 5.41 months, ten implants (seven patients out of ten) were examined and all but one patient showed a marked improvement in HHS (the average increase was 127.9%), with no further progression of the disease.
Our recurrent behavioral assessment of Cra1/+ mice shows an early onset, stable phenotype of hindlimb cramping and impaired grip strength, with no further progression in adulthood over the 24 months of testing.
All of the progression appeared to occur within the first 20 weeks, with no further progression evident after 20 weeks.
This difference suggests that the mRNA pool represented in the pH-shift library is consistent with a further progression into the developmental pathway leading to mature bradyzoites.
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