Sentence examples for with favourable safety from inspiring English sources

Oral capecitabine (Xeloda®) is an effective drug with favourable safety in adjuvant and metastatic colorectal cancer.

In conclusion, this first phase II study of S-1 in irinotecan- and oxaliplatin-pretreated colorectal carcinoma demonstrated high-dose intensity, promising efficacy and survival with favourable safety profile.

In the field of RNAi therapy, the introduction of AAV vectors with favourable safety profiles has nevertheless allowed to use the powerful approach of RNAi for successful therapy of both systemic and local diseases in vivo.

Although the survival benefit conferred by sorafenib in advanced HCC is an encouraging development, there is still a substantial unmet medical need for effective treatment options with favourable safety profiles in this difficult-to-treat population.

Capecitabine is an oral agent providing chronic dosing that mimics continuous infusion 5-FU with a favourable safety profile compared with bolus intravenous 5-FU/LV (Hoff et al, 2001; Van Cutsem et al, 2001; Cassidy et al, 2002).

Both exenatide twice daily and exenatide once weekly have been demonstrated to improve glycaemic control in patients with type 2 diabetes, with a favourable safety and tolerability profile [ 2– 6].

In conclusion, telatinib is an orally available small-molecule inhibitor of VEGFR-2/-3 and PDGFR- β tyrosine kinases with a favourable safety profile in patients with refractory advanced solid tumours.

In summary, the results of this phase II study demonstrate that capecitabine plus paclitaxel is highly effective with a favourable safety profile in patients with anthracycline-pretreated advanced/MBC.

Recently, six patients with localised scleroderma (linear and plaque scleroderma, generalised morphea) have been locally treated with in vitro expanded autologous ADSC with a favourable safety profile and a significant improvement in the skin, at 1-year follow-up.

These results, together with the favourable safety and tolerability findings, are consistent with previous long-term studies of esomeprazole for prevention of pre-specified GI symptoms and peptic ulcers in European and North American patients receiving NSAIDs [ 12, 13].

6 AIT can lower IOP in most types of open-angle glaucoma with an intact downstream drainage system and do so with a favourable safety profile.