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Morula production rate was also higher (P<0.01) for good as compared with fair quality oocytes.
Heterogeneity was assessed using the Q statistic and I. Results 48 studies with fair quality, enrolling 1 896 859 patients, were included in the meta-analysis.
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All papers were rated as fair quality with the exception of one paper [ 33] that was rated as good quality.
All reviews judged the primary research studies to be of least fair quality with a low risk of bias.
For the most part, evaluations of characteristics were rated as being of "good" or "fair" quality, with only 69 of 229 (69.9%) evaluations rated as "poor".
Evidence synthesis of the WLQ resulted in moderate negative evidence for hypotheses testing (three studies with fair methodological quality and two with poor methodological quality and only 60% of the results were in accordance with the hypotheses).
There were several fair quality trials with limited information on steps to ensure adherence to the intervention protocol.
In the current review, only studies of at least fair quality (i.e., with an average quality score ≥2.0) are included in the analysis.
Secondly, compared with studies of good quality, those of fair quality showed a stronger association between reduced eGFR and stroke.
Models 1, 3, 4 and 6, and Models 5, 7 and 8 generated two and three clusters, respectively, with fair cluster quality and similar profiles.
Thirty studies were deemed to have fair quality (low to moderate risk of bias, with 8 or more points on the quality scale).
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