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Murine monoclonal antibody GNC92H2 was elicited by active immunization with a cocaine immunoconjugate and binds free cocaine with excellent specificity and moderate affinity.
Atomic force micrograph (AFM) images show that the nanorod-bound DNA is recognizable with excellent specificity, indicating the potential use of such material as a versatile gene delivery carrier in gene-based disease therapy.
Conclusions: The developed method is very simple and rapid with excellent specificity accuracy and precision which can be useful for the routine analysis and quantitative estimation of puerarin in plant extracts and formulations.
The biosensor operated without time-consuming and tedious procedures (e.g., sample pretreatment, long and multiple incubations, washings) was able to accurately quantify trace levels of norovirus GII capsid with excellent specificity and reproducibility.
SA-FSNPs were able to detect aptamer-labeled hepatoma cells with excellent specificity and good sensitivity, and they emitted strong, photobleach-resistant fluorescent signal.
Increasing the number of assay replicates tested resulted in high sensitivity for CRC with excellent specificity in healthy controls.
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In comparison to PHQ-9 "depressive mood", sensitivity was low (46%) with an excellent specificity (94%), (PPV 76%; NPV 82%; LR + 8.04; LR-.572, ROC area.702).
The former is suitable for screening, with its high sensitivity and good NLR, while the latter is suitable for definitive diagnosis of infection, with its excellent specificity and good PLR.
They show that the RBH method combines a good sensitivity (about 70% of the orthologs are detected) with an excellent specificity as the number of confirmed orthologs reaches ∼95%.
As for intraoperative evaluation of PJI, we found that real-time PCR is useful for screening of infections, with its high sensitivity and good negative likelihood ratio, while histopathological evaluation is suitable for definitive diagnosis of infection, with its excellent specificity and good positive likelihood ratio.
In general, the MoCA yielded higher AUCs (0.891) with favorable sensitivity (78%%) and excellent specificity (94 %) compared with the MMSE in differentiating the participants with and without dementia in either the total sample or all subgroups.
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