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With every division there are imperfections.
A decade later a hypothesis was put forward: telomeres – repeated DNA sequences at the ends of our chromosomes – shorten with every division, and when they get too short, divisions stop and the cells die.
With every division, there's a risk of a cancer-causing mutation in a daughter cell.
With every division there is an increasing chance of cells entering cellular senescence, and never dividing again.
With every division of somatic cells in culture, and presumably in vivo, telomeres progressively shorten by 50 200 bp until one or few telomeres become dysfunctional.
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This label is inherited through successive cell divisions, and with every cell division, each of the two daughter cells receives approximately half of the label [ 35].
The duo entered the conference room to find it packed with members of every division: creative types, media buyers, production people.
Both of these family trees indicate the existence of multiple members in the common ancestor by having multiple supported clades with members from every division of the plant lineage.
"I could play in every division with this club and I'm proud of it.
In the first half Smiths' management delivered margin improvement in every division with group operating margin improving 190 basis points year on year.
Based on a 50% (0.33 log10) decline in H2B-GFP levels with every cell division (supplementary material Fig. S2F,G), ∼40% of the SC pool undergoes ∼2 divisions (LRCs), whereas the remainder undergo ∼4 divisions (nonLRCs) between E16.5 and P1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com