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Unlike other plant type II PLP decarboxylases, plant AAADs have undergone additional functional evolution resulting in multiple paralogs with divergent functions [ 10].
We show that the presence of microbes induces the expression of plant enzymes with divergent functions, such as cellulases and cellulose synthases, and this suggests that the uptake process consist of a succession of distinct and tightly regulated processes, which would exclude the possibility of permanent induction of genes.
The structures of proteins with divergent functions are very similar.
Different snRNA isoforms might form structurally distinct snRNPs with divergent functions.
Within this cytoskeletal regulatory network, the set of genes targeted by miR-142-3p miR-142-3p miR-142-3pith divergent funcontains
Expanded genes might give birth to new genes with divergent functions for better adaptability, competition for species existence.
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There is little precedent for what to expect, however, variation in pattern formation could be controlled by a number of cis-regulatory elements of a single gene, clusters of duplicated genes with divergent function, or clusters of non-paralogous but functionally-related genes.
The convergence of the mechanism of action, together with their divergent functions, offers a possible protocol for studying these features of aaRSs in general.
Using sequence similarity networks (SSNs), the members with these divergent functions could be separated into isofunctional clusters.
The identified outlier genes code for proteins with highly divergent functions (additional file 4), suggesting that directional selection for local adaptations in cod occur along multiple environmental dimensions.
These seemingly non-paralogous loci, together with the divergent functions of the T6SS suggests that this secretory system could influence a variety of interactions within a single species, with various hosts, and/or with other bacteria occupying the same niche [ 3].
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