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Conversely, divergent CTCF binding between species is correlated with divergence of internal domain structure, likely driven by local CTCF binding sequence changes, demonstrating how genome evolution can be linked to a continuous flux of local conformation changes.
Furthermore, for duplicate genes, expression differences are positively correlated with divergence of cis-regulatory motif(s) [50], although changes in other factors, such as mRNA stability and chromatin structure, can also be responsible for expression differences.
Phylogenetic analysis based on comparison of 16S rRNA sequences indicates that members of the family Leptospiraceae form the deepest branch in spirochete evolution, with divergence of saprophytic and pathogenic Leptospira likely being the result of a single event [13].
The four MD conformations show the PhC phosphate either close to tyrosines at the binding sites in Fig. 4 A and C or close to tyrosines in its outer rim in Fig. 4 B and D. As discussed above, the anomalous PhC position in PDC109/a of protomer A in the crystal structure (Fig. 4 E) is also consistent with divergence of the distances in the MD simulations (left column in Fig. 3).
The divergence among other viruses was incongruent with divergence of host species, e.g., those from S. kuhlii and Myotis ricketti.
In particular, domestication, as a special selection, has played important role in crop cultivation with divergence of many genes controlling important agronomic traits.
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That part specifically included two of the branch points for which there are dates associated with divergences of plant lineages (of Triticum from Hordeum and of Triticeae from Aveneae).
Early and rapid gene loss was also found in another lineage of Buchnera with divergence dates of 80 150 My [30], [31].
The number of orphan reactions is also shown in Figure 2 and increases with divergence time of the ancestral node.
It is found that instruments with divergence requirements of ±1.0° will have excellent neutron transport with a 3×3 cm2 pinhole, while lower divergence requirements of ±0.5° can do with a smaller pinhole of 2×2 cm2×2
This figure seems to be in agreement with divergence times of about 12 14.3 million years for the cattle-caprine lineages, as suggested from genetic and morphological data [32].
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