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The workshop recognized the specific complexity of testicular function exemplified by dedicated cell types with distinct functionalities, as well as different cell compartments in terms of microenvironment and extracellular matrix components.
We argue that zinc regulation is not only tissue-specific but also time-dependent, such that groups of genes with distinct functionalities may be regulated at different time-points following a change in zinc availability.
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Despite the significance of Extract Method refactoring towards code quality improvement, there is limited support for the identification of code fragments with distinct functionality that could be extracted into new methods.
Cell type specific gene expression is an inherent property of all multicellular organisms and indeed represents a major determinant that underlies the generation of differentiated cell types with distinct functionality.
More generally, we suggest that molecules with three distinct functionalities may represent a practical upper limit on the extent of functionality present in the platform molecules that serve as the bridge between biological and chemical catalysis.
We have also introduced the reason for investigating the phosphorylation of three tyrosine residues with the distinct functionalities of autocatalysis, signaling and trafficking.
From this we observe a non-uniform distribution of human interactions with HIV proteins, suggesting distinct functionalities (see Figure 2-A).
In general, our data correlate well with the distinct functionality of the full-length receptor tyrosine kinases and their respective intracellular domain (ICD) proteolytic fragments.
Our results lend support to a DNA damage-independent function of PARP-1 sumoylation and suggest a mechanism for how the distinct functionalities of the polymerase could be delineated through its interactions with relevant forms of DNA.
The structural comparison of AsCpf1 with Cas9, a type II CRISPR-Cas nuclease, reveals both striking similarity and major differences, thereby explaining their distinct functionalities.
These composite particles offer two distinct functionalities: an inner Fe3O4 core, which gives the composites strong magnetic properties, making them easy to manipulate magnetically, and an outer Y2O3 Tb3+ shell with strong luminescent properties.
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