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"We need to put in place more advanced return systems for products such as garments, electronics and rare earth minerals, which today's return systems can't handle", says Block. "And we need to design our products with disassembly as the end goal.
The use of sensor-embedded products (SEPs) is a promising approach in dealing with disassembly.
The existence of non-functional components further adds to the uncertainty associated with disassembly yield.
In each case though the order of events remains the same, starting with disassembly of endothelial cells from parent vessel, rearrangement and formation of new vascular plexus (Madri and Pratt 1986).
Because most glomerular diseases involve dysfunction of podocytes along with disassembly of slit diaphragms [1] [5], it is necessary to understand the molecular basis for the maintenance of slit diaphragms.
Sporozoite conversion into liver stages requires initial remodelling of the parasite pellicle, with disassembly of the inner membrane complex (IMC) and appearance of a bulb that progressively enlarges until the initially elongated sporozoite has transformed into a round form [28], [30].
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The state of the vimentin appears to be governed by phosphorylation and dephosphorylation events [ 29], with vimentin disassembly associated with phosphorylation [ 30].
In summary our data suggest that in pancreatic carcinoma cells activated Rac1 interacts with IQGAP1, which is associated with a disassembly of E-cadherin-mediated adherens junctions and with increased cell migration and invasion of pancreatic carcinoma cells.
These results indicate that active Rac1 destabilises E-cadherin-mediated cell-cell adhesion in pancreatic carcinoma cells by interacting with IQGAP1 which is associated with a disassembly of E-cadherin-mediated adherens junctions.
Metastasis of carcinoma cells often commences with the disassembly of junctional complexes and downregulation of other epithelial traits coupled with the acquisition of a migratory and invasive mesenchymal phenotype (so-called epithelial-mesenchymal transition [EMT]).
But the idea stays with me — disassembly matters every bit as much as assembly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com