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In fact, minor myelin swelling is observed with diminished effect over time.
Some studies have found no reliable relationship between quality score and effect size [ 10- 12] and another has found that low study quality was associated with diminished effect sizes [ 13].
In multivariate regression only duration of follow-up remained significant (β coefficient for regression −0.04 (95% CI −0.08 to −0.004) p=0.03) with diminished effect of intervention at extended follow-up.
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This presented as a large deviation for both hits and CRs relative to baseline from 150 ms onward, with a diminished effect for hits relative to CRs.
Cortactin and FADD (Fas-associated death domain) over-expression was linked to CCND1 amplification, determined by fluorescence in situ hybridization, but was not associated with a diminished effect of tamoxifen.
This enhancement was eliminated in patients with left TLE for words and those with right TLE showed a diminished effect for faces.
The weight of evidence to date indicates a potential for benefit in the older people, and there is no a priori reason to suspect a diminished effect compared with younger people.
7– 10 Endogenous GLP-1 has a short half-life of 1 2 minutes and a diminished effect in patients with T2DM.
Since OS participants on HT began HT several years before enrolment, a diminished effect of HT with time could explain an OS/RCT difference.
The model size should be moderate with diminished boundary effect on the simulation results.
As TCF7L2 rs7903146 has been associated with diminished incretin effect we investigated whether interaction between dietary intake of carbohydrate, fat, protein or fibre and this variant affects the risk of type 2 diabetes.
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