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Examination of agonist-bound GPCR structures reveals that GPCRs exist in conformations with differing extents of TM6 movement, with no or little TM6 movement for inverse agonists and larger TM6 movement for partial agonists and full agonists.
Patients were subdivided into one of four groups according to the size of the calcification cluster and the pathology was reviewed to investigate the likelihood of diagnosing malignancy, either in situ or invasive, with differing extents of radiological abnormality.
(A ) Variation of metabolite levels across glycolysis over 14 conditions in triplicate resulting in 42 independent experiments involving cells growing in basal conditions and those with differing extents of inhibition of glycolysis from results in Figure 4. (B ) Simulated distribution of FBP levels in glycolysis.
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Results presented here indicate that under mild conditions cellulose and hemicellulose are hydrolysed to differing extents, with hemicellulose hydrolysis predominating.
e Structurally, we could envisage the template bases A, C, G, and T being sequestered in the pocket between helices O and O1 to differing extents, with A being the most buried (therefore least available for stacking) and G the least.
When we docked the antimalarials and SERMs into a representative VP35 structure these compounds were found to overlap with the X-ray ligand to differing extents.
Those systems may be designed specifically to treat the differing extents of LSCD, with combined delivery of drug and cell therapies.
Frum and Reich are, to differing extents, concerned about the Afghanistan mission.
I struggle with differing opinions.
Third, the surgical extent differed, especially with respect to the extent of lymph node dissection.
Ischemic changes were observed in the spinal cords of both laminectomy and syrinx rats but restricted to cells with neuronal morphology, differed in an extent between laminectomy and syrinx rats.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com