Sentence examples for with different ancestries from inspiring English sources

Some of the admixed strains also exhibit high rates of heterozygosity, indicating a relatively recent mating between strains with different ancestries.

It could also be hypothesized that in Caucasians the T allele for rs10880 might be in stronger LD with another unrecognized, functional variant, than in patients with different ancestries.

Conversely, the number of interactions involving proteins encoded by genes with different ancestries is significantly lower than expected at random (P < 2 × 10−4 for the archaebacterial eubacterial, archaebacterial ESP, and eubacterial ESP classes; supplementary table S7, Supplementary Material online; fig. 1).

We also identified a second Hcp upstream of this conserved locus (NRG_01080) that is 100% identical to Hcp in E. coli S88 (O45 K1 H7) that causes neonatal meningitis [ 44], suggesting that this T6SS island is a mosaic with different ancestries.

If an associated allele is shared between groups with different ancestry, the differences in LD between populations, such as European and African, can be useful to help fine-map the locus by restricting the credible set of variants to those that are in LD with the causal variant in all populations (2).

This is especially true in cases where disease risk differs between groups with different ancestry.

Assigning DEFA1A3 class to haplotypes within the 1000 Genomes project highlights a significant difference in DEFA1A3 class frequencies between populations with different ancestry.

Analysis of associations using subjects with different ancestry, combined with bioinformatic and genomic characterisation, can provide strong evidence for the likely causative alleles and their functional basis.

Third, if cohorts with different ancestry are genotyped on different platforms it might be difficult to distinguish the two confounding factors, platform and population stratification.

The low-coverage 1000 Genomes approach, which generated whole genome sequencing data of 179 individuals with different ancestry (YRI, CEU and EAS), is estimated to have relatively low power to detect singleton SNPs or rare variants [ 23].

While the description of a triallelic variant might have a relevance for future association studies in populations with different ancestry, its location in the network suggests that the site is neutrally evolving.