We discuss these design issues with consideration of data from the United Kingdom infantile spasms study (UKISS) – in which neurodevelopmental outcomes show evidence of an interaction between underlying etiologic classification and randomised treatment – and with consideration to proposals on study design from the recent consensus statement of the West Delphi group.
Thus, data on TNM stage should be used with caution in epidemiological and other research, with consideration of missing data according to age and level of comorbidity.
Give special consideration to agents with data supporting safety in routine surgery and efficacy in adhesion prevention.
ASPs are often based on the best-available evidence, with consideration of local data on antimicrobial resistance, and primarily seek to reduce morbidity and mortality in patients for whom the protocols were designed.
However, large roughness values give too much weight to measurements with no consideration to global trends in data (Inoue 1986).
In this study, fatigue life of welded joints is predicted based upon Miner's damage rule and the histogram of stress range frequency with consideration of traffic data.
Specification of hypotheses/predicted outcomes and expectations of the test, along with consideration of what data, how it will be collected, and by whom, should be addressed as part of the plan stage.
Most criteria reflecting the internal validity of studies were met by a majority of studies, with the exception of three internal validity criteria: retention, reporting a rationale for sample size and conducting analyses with consideration for missing data that maintained the fidelity of the randomisation.
Ultimately, we feel that the complexity of antibiotic regimens speaks to clinical uncertainty and the urgent need to improve the yield of ascitic cultures and tailor therapy for SBP with consideration of local microbiological data.
eXtasy is another recently published solution that uses phenotype comparisons along with consideration of many other data types (Sifrim et al., 2013).
Therefore, we are encouraged that we likely have an overall improved assessment of phytoestrogen intake with consideration of series II data.
