Sentence examples for with consequent development from inspiring English sources

Multi-centre and multi-site clinical drug trials in pregnancy, coupled with HIV testing, are urgently needed to determine drug response in HIV-infected pregnant women with consequent development of appropriate drug policies.

This leads to tolerance breaking to this self-protein with consequent development of anti-IFI16 antibodies.

Its overexpression, cytoplasmic mislocalization and extracellular appearance during cell death lead to the breaking of tolerance to this self-protein with consequent development of anti-IFI16 antibodies [ 13].

The pathogenesis of RT-induced cystitis originates as a progressive obliteration of the small blood vessels of the bladder wall with consequent development of hypoxia and tissue damage [ 41].

Appropriate expandability of adipose tissue (AT) is necessary for preventing ectopic deposition of lipids and their metabolites in tissues such as muscle, liver and pancreas, with consequent development of insulin resistance [ 10– 13].

However, over time, beta cells fail to secrete insulin normally and can no longer compensate for the decreased tissue insulin sensitivity, with consequent development of impaired glucose tolerance and eventually type 2 diabetes.

Andrea Dunaif (Chicago, IL) noted that the major factors giving rise to polycystic ovary syndrome (PCOS) are metabolic, in association with insulin resistance and obesity, with the consequent development of hyperandrogenemia and anovulation affecting 7% of premenopausal women.

Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by a perturbation in surfactant homeostasis, resulting in its accumulation within alveolar spaces, with a consequent development of severe hypoxemia.

In addition, expression of AIRE and PTAs were significantly reduced in TRAF6-deficient mice, with the consequent development of an autoimmune phenotype 166.

Upon the subsequent onset of spermiation, epididymal obstruction ensued, with the consequent development of spermatic granulomata, back pressure-induced atrophy of the seminiferous epithelium, orchitis, and fibrosis of the testicular parenchyma.

The giant liver fluke (Fascioloides magna) is a parasite which, contrary to other liver flukes of ruminants, exists as parasite in the hepatic parenchyma of domestic and wild ruminants, where it inflicts damage to all liver structures with the consequent development of liver fibrosis and cirrhosis.