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Many types of proteins express their functions with conformation change in various biosystems.
Xing, K. et al. Triple helical molecular braid and parallel packed wavy chain-based supramolecular organic frameworks with conformation- and packing-dependent luminescent properties.
ss-siRNA action requires a 5′ phosphate to achieve activity in vivo, and we developed a metabolically stable 5′-(E -vinylphosphonate (5′-VP) with conformation and stE -vinylphosphonateerties similar to the natural phosphate.
Teal sticks represent ligand conformations at different Shaker stages starting with the conformation right after Wrapper (1), and continuing with conformation after MDBSA (2), and after MDF (3).
RA-X (77) containing a glutamic acid at residue 2 possessed strong antitumour effect on P388 while RA-IX (76) with conformation restricted to a type II β-turn at residues 2 and 3 showed almost no antitumour activities [43].
These hybrids share basically the genes from the species of S. officinarum and S. spontaneum and are complex aneuploidies with conformation of 2n + n, i.e., with total fixation of the chromosomes of S. officinarum and half of those of S. spontaneum, besides having combined chromosomes [61],[61].
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Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies.
Flow cytometry with conformation-specific antibodies revealed the Cys-loop in two [(L4T4 2 and (L2T2 4] and the helix conformation in one [(H2T2 4] of the different permutational constructs.
In this study, we represented the native and denatured states atomistically, with conformations sampled from explicit-solvent molecular dynamics simulations at room temperature and high temperature, respectively.
AGP would behave in solution as a branched or hyper-branched polymer with conformations ranging from globular to elongated shape depending on the size of the carbohydrate branches.
Briefly, 150 250 µg of total cell extracts were immunoprecipitated with conformation-specific monoclonal PAb240 (mutant specific) and PAb1620 antibodies (Calbiochem).
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