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Although all registries provided staging information, there were 13,456 cases (44% of total) with complete stage information.
For those patients with complete stage of tumour recorded, more aggressive cancers were not related to deprivation category.
The cases with complete stage information were used to derive data sets with simulated missing stage information.
Abbreviations: NOS = not otherwise specified; RS = point estimates of relative survival ; SE = standard error (percent units); a unstable point estimates of RS (SE > 5percentt units) were not reported; b % of histology; c % of those with complete stage information; d % of cases without stage information.
Abbreviations: NOS = not otherwise specified; RS = point estimate of relative survival ; SE = standard error (percent units); a restricted to cases with complete stage information; b the differences between RS (percent units) were tested using model-based period analysis; c including other adenocarcinoma; d including carcinoma NOS.
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No significant difference in overall outcome was found between patients with incomplete staging and those with complete staging [ 18].
There are no specific case series or randomized trials investigating pure serous EIC, hence, it is vital to manage this early stage malignant disease aggressively with complete staging, even if the lesion is limited to a polyp.
The cases with complete tumour stage information were extracted and their stage information partly removed according to a MAR missingness-pattern, resulting in five simulated data sets for each cancer entity.
With stage one complete, we're now setting out to complete stage two: the official legal undertaking, which involves a simple ceremony and form-signing in the registry in Douglas.
The proportion of unknown disease stage was hence worst in the early 1990s, only 52% with complete clinical staging for cases in 1990 to 1994 (P < 0.001), and this improved in the last 5 years of the study.
The breast nodule was subjected to fine needle aspiration biopsy (FNAB) which revealed atypical cells, following which the patient underwent baseline blood workup and complete staging with computed tomographic (CT) imaging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com