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"Someone that I met with characterized it as white-collar street crime".
Here, we make use of a framework that treats intracellular signal transduction networks as "black boxes" with characterized input-to-output response relationships.
It also induces growth arrest with characterized morphological changes and loss of mitochondrial membrane potential (MMP) in a concentration dependent manner.
Here we evaluated the effect of sunitinib on MPNST cell lines with characterized 4q12 amplification status, protein and transcript levels.
Most of the genes identified here seem to encode short peptides, and five out of the seven deduced proteins with characterized structural motifs contain nucleic acid-binding domains.
As the majority of these ORFs have no homologs with characterized sequence or protein structure, traditional sequence-based approaches cannot be applied to deduce their biological function.
In this study we used animals previously generated in our laboratory with characterized mutations in the intracellular domain of the GHR [19] (Figure 1).
Further, MYB29 and MYB76 show co-expression with characterized and predicted aliphatic glucosinolate genes in the ATTED-II public database (Table S4).
This list of 63 candidate genes was next filtered to identify genes whose expression correlated with characterized genes of the aliphatic glucosinolate biosynthetic using the public co-expression database ATTED-II (http://www.atted.bio.titech.ac.jp/) (Table S2).
To predict which genes are under H-NS control in CAP, putative binding sites were identified by comparative analysis with characterized H-NS binding profiles in related model proteobacteria (see methods).
Prominent members of this family with characterized roles in inflammatory and innate immunity are the toll-like receptors, which are comprised of ten members in humans, with homologs for all encoded in the zebrafish genome [28], [29].
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