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Meta-analysis was not possible due to extremely heterogeneous data from the studies included, with categorisation of both the outcomes and exploratory variables differing between the studies.
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"With the categorisation of the academies, everything is positive now.
But even with this categorisation of the problem area, defining what is precarious or not continues to be a complex issue.
For 16 of the 18 criteria, agreement with the categorisation of the criteria into the high, intermediate and moderate categories was high at ≥ 70% (10 had agreement ≥ 80%).
The disadvantage of grouping is that associated with any categorisation of a continuous variable [ 21]: information is lost, particularly at extreme risks.
Of interest in particular for this study was the relationship of age group with the categorisation of high versus low/moderate dental anxiety.
The cross-tabulation of educational level appeared not to be associated with the categorisation of those into the two dental anxiety groups (high versus moderate or low).
To assist with the categorisation of co-expressed genes and partitioned modules according to their potential function or processes, we assessed the modules for enrichment primarily for GO terms in R (http://www.r-project.org) using the 'gProfileR' package [ 37] to interface g:profiler (http://gprofiler.at.mt.ut.ee/gprofiler/).ee/gprofiler/
With the categorisation of the cumulative life doses, the zero group (no exposure at all) was defined as a separate category; the remaining values were then divided into two groups (median split) or into three groups (tertile split), depending upon the remaining group size.
40 However, for the sake of comparison with a recent Danish case control study, 22 we performed secondary analyses with the same categorisation of the antidopaminergic drugs.
†Test for homogeneity with categorisation in three groups of underlying disease (appendicitis, mesenteric lymphadenitis, other disease).
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