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11 38 However, it is believed that patients are likely to refuse ocular surgery due to rumours of failed surgeries within small communities 39 and because glaucoma surgery is associated with appreciable risk and will not improve vision.
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The Environmental Protection Agency has calculated that adults and infants can consume 50 micrograms of BPA per kilogram of body weight every day over a lifetime with little appreciable risk of harm.
RfDs and RfCs are supposed to represent lifetime inhalation or ingestion exposure with minimal appreciable risk, but they do not include information about the estimated risk from exposures equal to the RfD/RfC.
Perhaps banks should produce such specific data voluntarily, so that we actually see that their private equity investments do, in fact, generate significant public benefits with no appreciable risks.
The radioactive dose was chosen to be detectable by AMS without appreciable risk to volunteers consistent with the policy of utilizing doses as low as Reasonably Achievable (ALARA) or Practical (ALARP).
For instance, in node-positive tumours the group with low EP may be at lower but still appreciable risk of relapse.
The RfD is an estimate of the daily exposure to children and adults that is likely to be without appreciable risk of deleterious effects during a lifetime, with uncertainty spanning perhaps an order of magnitude.
10 The Swedish study suggested an appreciable risk of glioma within 10 years of exposure.
The RfC is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without an appreciable risk of deleterious effects during a lifetime.
MRLs are estimates of daily human exposure that can occur without appreciable risk of human health effects.
There is therefore a need to decide what constitutes an appreciable risk or the desired level of protection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com