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However, with alternate technologies such as microarray expression analyses, genetic function can be directly linked regardless of knowledge of the individual's genotype [ 23].
The two alleles satisfied multiple criteria for disease causation: both were validated with alternate technologies; the nonsense p.R954X allele had been previously reported in unrelated CMT families and corroborated with functional studies; each segregated faithfully in the pedigree and no other lesion was discovered in the locus despite adequate coverage of all coding bases with NGS reads.
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Sequencing with an alternate technology is, nevertheless, the most statistically correct approach for validation, provided the alternate sequencing methodology employs a different approach from the original technology, with a different spectrum of biases, error modes or other limitations.
Based on relative benefits and costs, relationship lending may be best suited for some types of SMEs, with alternate lending technologies better matched to others.
The WES and WGS replicates used in different experiments are listed in Table 4, with all replicates used for concordance testing against alternate technologies and curated variant sets.
You also have new technologies coming in, demand response, alternate technologies, batteries.
CNVs identified using WaveCNV were verified using three alternate technologies: Nimblegen, 2.1 million CGH tiling array, Illumina 1 million Omni-quad SNP array and verification of 80 CNV loci with copy number varying from 0 to 30 using qPCR.
This reduced the complexity of the transcript population, facilitated the identification of differential transcript processing, allowed clustering of similar expression profiles and simplified comparisons with expression data generated using alternate technology platforms.
Verizon, which operates in 29 states, Washington and Puerto Rico, attributed the cutback to the slumping economy, consumers' use of alternate technology and losses associated with the mandated sale and lease of its telecom network.
There is competition from VCRs & videocassettes, alternate technology like SMATV.
With the rise of eCommerce, usually under the aegis of the marketing department, came the rise of an alternate technology organization, not tied to the CIO.
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