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Usually, a suboptimal study requires a repeat study with additional bolus of contrast.
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Adrenaline was administered as a continuous infusion at a rate of 1 μg/kg/minute with additional boluses of 1 or 3 mg if the mean blood pressure fell below 50 mmHg to ensure sufficient blood pressure and, therefore, CPP.
After transseptal access, a bolus of intravenous heparin (5000 IU) was administered, with additional bolus to maintain an activated clotting time ≥200 s in the first 18 patients and ≥250 s in the rest.
Administration of IDegAsp at a single meal, with additional bolus injections at the remaining meals, facilitates a treatment regimen that requires fewer daily injections than standard basal-bolus therapy, which typically requires 4 5 daily injections.
The standard regimen uses an 85-U/kg bolus of UFH if there is no platelet glycoprotein IIb/IIIa (GpIIb-IIIa) inhibitor or 60 U/kg if GpIIb-IIIa inhibitor use is planned, with additional bolus guided by blinded ACT measurements.
With insulin glargine, an additional bolus of rapid-acting analog 2 3 h after lunch can be given (21); this was not part of the protocol of the present study.
Surviving animals then received a 3.0 mg/kg additional bolus of verapamil.
Only the six HIET-treated animals survived the additional bolus of verapamil.
†Sum of basic fentanyl infusion with additional boluses; *administered during the 48-h resuscitation period; ††sum of Ringer's lactate and hydroxyethyl starch; ╫final balance = (Ringer's Lactate basal infusion + glucose 50% basal infusion + Ringer's lactate bolus + hydroxyethyl starch bolus) - (urine output + gastric tube output); aone-way analysis of variance (ANOVA).
Local Infiltration Analgesia (LIA) could be given as infiltration of a mixture of 100 mL ropivacain 2 mg/mL, ketorolac 15 mg, and epinephrine 0.25 mg given at the end of surgery with additional boluses given eight and 16 hours postoperatively via a catheter placed within the joint capsule.
Additional boluses of 1 × 105 tumor cells were injected subcutaneously in the left and right flank.
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