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In this work, a Lexicographic Goal Programming problem modeling this integration is introduced, together with a solving strategy.
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Unfortunately, we could not identify any homologous proteins with a solved crystal structure in extant databases (see Materials and Methods).
We compared docking performance to that of the empirical screen on a set of 20 HADSF members with a solved unliganded crystal structure (Table 1).
As the database of in meso structures grows, data mining should provide guidelines for rationally choosing host lipids based on a target's homology with a solved structure or a predicted membrane topology.
Notably, all of the 33 enzymes with a solved 3-D structure have been assigned to a subfamily, resulting in thirteen individual subfamilies out of 51 with at least one structural representative.
When each algorithm is applied properly for each step you will end with a solved cube.
"Finding good photos is a solved problem with AI.
My business background coupled with my agency experience allows me to really marry an idea with solving a business problem in that way.
Phases were obtained by molecular replacement with a previously solved ubiquitin structure (PDB ID: 1UBQ) 20 as a search model.
"Innovation starts with a vision for solving a problem in the marketplace," said Gruber.
There are 3 families of PyrD, each with a different solved quaternary structure [ 33].
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