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Increased TIMP-1 expression was inhibited by XYXD, with a significantly reduction at the 5 and 25 μg/ml dose level in GFP-Col-HSC cells (Fig 5b) (P < 0.05 or 0.01).
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A study among the Japanese obese patients with T2D also found a significantly reduction in LDL-C with liraglutide at 6 months after discharge [ 35].
A report of conference proceedings describing a subgroup of patients with migraine with aura enrolled in a double-blind placebo-controlled trial ("almost one-third" of 211 patients) (Freitag 2003) reported that topiramate treatment was associated with a significantly greater reduction in the occurrence of photophobia compared with placebo (41% reduction vs 15% reduction, P=0.02).
Furthermore, JHD2 overexpression caused a decrease in H3K4me3 at both NTS regions, with a significantly stronger reduction at NTS1 compared with NTS2.
Both in the 1 Hz and the 25 Hz group the number of headache days per 28 days decreased significantly by 7.0 and 3.3 days, respectively (PP-analysis, Table 2), with a significantly larger reduction in the 1 Hz compared to the 25 Hz group (p = 0.035).
KLK13 positivity is associated with a significantly large reduction in risk of relapse and death.
Liraglutide was also associated with a significantly greater reduction in fasting plasma glucose and postprandial glucose in this trial.
Venous outflow and venous capacitance were significantly reduced in both legs postoperatively compared with preoperatively, with a significantly greater reduction in the ipsilateral limb.
Blood β-hydroxybutyrate followed a similar pattern with a significantly greater reduction (P < 0.05) of the ketone body with increasing doses of glargine (supplementary Fig. 1).
It was hypothesised that lavender would be associated with a significantly greater reduction in selected behaviours than a neutral control oil.
Treated with pioglitazone, type 2 diabetes mellitus (T2DM) patients with the ADIPOQ C- 11377 CC genotype were associated with a significantly smaller reduction in glycated haemoglobin (HbA1c) compared with the minor G allele carriers [ 21].
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