In contrast, DDR1-IN-2 is considerably less selective with a selectivity score (S(1) at 1 μM) of 0.07 and potential additional targets including Abl, BLK, CSK, EGFR, LCK, and PDGFRβ (Supplemental Tables 3 and 4).
Compound 6, however, showed the most selective trypanocidal activity with a selectivity index of 9.8.
The experiments showed that the material could selectively adsorb phenylalanine (Phe) with a selectivity (d/l) of 1.25.
However, bisphenol AF emerged as a ligand selective for ER-α with a selectivity ratio of 0.15 (Table 3).
Four of the isolated compounds 2, 3, 6 and 7 exhibited moderate trypanocidal activities with IC50 values ranging from 4.7-13.8 μg/ml, however, selectivity versus mammalian L6 cells was completely missing for 2, 3, and 7. Compound 6 showed the most promising and selective trypanocidal activity (IC50 = 4.7 μg/ml) with a selectivity index of 9.8.
The silicon etching rate is 80 nm/min with a selectivity Si HSQ = 2 1.
YM53403 displays an EC50 of 200nM with a selectivity index of 412.
Hydrogen is the main product with a selectivity around 55 60%.
Among all possible couples of thresholds, the S ratio selected RAP < 10 mmHg as predicting ΔLVSW > 42 g.m. with a selectivity of 0.63 and a specificity of 0.61.
Cr Si-2 moleCr Si-2ieve catalyst with 1.28 wt% chromolecular 45.5% ethylene yield with a sievetivity of 87.9% at 650 °catalyst
In the 3,4-dimethoxyacetophenone hydrogenation, 39% enantiomeric excess was obtained, with a selectivity of nearly 100%.
