Sentence examples for with a rac from inspiring English sources

Our results with a Rac inhibitor were analogous to results with a RhoA inhibitor on hippocampal LTP [20], suggesting that the small GTPases involved in the (multi-step) cytoskeletal re-arrangement associated with late phase LTP may differ between pyramidal and Purkinje neurons.

Bound Rac-GTP was detected with a Rac specific primary antibody and a HRP-conjugated secondary antibody.

Ben Godfrey spent the day with an RAC patrolman in the Midlands.

Drosophila Rac1 is a Rho GTPase family member that has a reported male semisterile phenotype that is enhanced in the presence of a mutation in cdi (center divided), a kinase that interacts with RacGAP84C (a Rac GTPase activating protein) (Raymond et al. 2004).

Moreover, BCR coexists with Tiam1 as a Rac GEF-GAP complex to regulate spine morphogenesis and synaptic plasticity under the control of BDNF-TrkB signals [ 19].

We determined the structure of the 23rd Ig repeat of FLNa (IgFLNa23) that interacts with FilGAP, a Rac-specific GTPase-activating protein and regulator of cell polarity and movement, and the effect of the three disease-related mutations on this interaction.

DMOG-treated endothelial cells exhibited a reduction of immunoreactive Rac-1 at the migrating front, concomitant with a diminished Rac-1 activity, whereas total Rac-1 protein remained unchanged.

Treatment with a specific Rac inhibitor (NSC-23766 [12]) also increased centrosome separation in prophase cells.

Following repeated dosing, PD 0332991 accumulated with a median Rac of 2.4, which is consistent with the t1/2.

Tiam1 interacts and cooperates with BCR (breakpoint cluster region), a Rac GAP at the synapse, and the two counteract each other on Rac1 activity and spine morphogenesis [ 19].

Active Rac binds PAK, which is not only a Rac effector but also interacts with PIX, which in turn stimulates Rac.