Sentence examples for with a high specificity from inspiring English sources

Nevertheless, recent progress has been made in the identification of compounds with a high specificity for PDE4B, PDE4D, or specific long PDE4D subtypes.

Site-directed mutagenesis of Gly567 to an alanine converted the dual positional specific LOX1 Md 1a to an enzyme with a high specificity for 9(S -hydroperoxide formation.

Functional evidences have shown that UGCAUG binds various tissue-specific isoforms of mammalian Fox-1 splicing factors with a high specificity [ 72, 73].

We observed that the majority of the plant specific tools may be made to predict targets with a high specificity in the model organism, A. thaliana if the parameters of predictions are optimized.

We have therefore generated an oligomer-specific IgM anti-Aβ antibody (OMAB) that binds Aβ oligomers with a high specificity and a high affinity, whereas its binding to Aβ monomers and dimers is comparatively weak.

It can discriminate UHRF1 DNA from three-base mismatched DNA with a high specificity.

In conclusion, the SAT assay is an accurate test with a high specificity and sensitivity which may increase the detection rate of HCV.

The findings of this study will be helpful to design an antibody with a high specificity and a high affinity to the antigen.

On the other hand, a fall risk assessment tool with a high specificity but too low sensitivity will result in many older people who actually are at high fall risk being classified as having a low risk of falls (false negative) and then miss the chance to undertake an in-depth examination56.

Magnetic resonance imaging represents a standard tool in knee evaluation with a high specificity and sensitivity in diagnosing meniscal tears.

Cutoff values of > 1.4 × 103 mm2/s for juvenile pilocytic astrocytoma and < 0.9 × 103 mm2/s for medulloblastoma have been suggested with a high specificity [47].