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There isn't one definitive way to come up with a good target.
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A protein-protein interaction involving one disordered partner and one structured partner has several features that are consistent with being a good target for drug discovery.
Although the frequency of wild-type p53 is unclear, RMS tumours with wild-type p53, with or without MDM2 amplification, are a good target for small-molecule inhibitors, potentially allowing for reactivation of protein signalling.
Hillary Clinton, with her cerebral hectoring, is a good target for such an attack.
The awaiting greeters are there to take down information from travellers who can connect them with companies who might be a good target.
Of the 95 colonies, 19 showed a good target recognition with binding ratios relative to a non-coated well of more than 2 (Figure 3C).
For example, given the implication of mu-opioid systems in binge eating [64], obese subjects with prominent binge eating could represent a good target population for opioid antagonists.
The overexpression of cyclin B1 as well as the cytoplasmic localisation in cancer cells compared with normal cells makes cyclin B1 a good target candidate for anti-cancer immune therapy.
Hyperlipidaemia-related factors might not be a good target for patients with HTN, and physicians need to recognise that patients with HTN in anaemia outpatient clinics might be potential CKD patients.
I had mentioned that the 1964 Olympics would be a good target to shoot for with a synchronous satellite.
The probability of having myocardial perfusion defects in an asymptomatic diabetic patient with DR was 11.7 [IC95%: 3.7-37] in comparison with diabetic patients without DR. Therefore, patients with DR are good target population for indicating SPECT.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com