A pancreatic enzyme preparation developed particularly for infants, Creon® for children (CfC), contains smaller granules to be administered with a dosing spoon (5000 lipase units per scoop).
The color of pharmaceutical dosage forms can be an important aspect of product branding and patient compliance with a dosing regimen.
To study the role of chemicals in this process, a TLF technique with a dosing system is required to add demulsifiers into already formed thin liquid films stabilized by interfacial layers formed from indigenous surface active molecules.
Herein, we present a modified design of the Scheludko-Exerowa cell with a dosing mechanism which allows for addition of desired chemicals to the intervening organic liquid film that is already formed.
For example, gemcitabine's anti-cancer activity is achieved with a dosing regimen that includes 1000 mg/m2 given once every week for seven weeks, followed by one week without drug and additional rounds of treatment as needed [22].
In order to facilitate administration of the drug, the nurses had been provided with a dosing sheet that showed the correct dosage for different bodyweights.
