Sentence examples for with a conformation of from inspiring English sources

The acidic non-enzymatic subunit comprises of extensive hydrophobic residues with a conformation of an anti-parallel β-sheets making it ideal for tissue specific targeting.

Thus, a model of the Ht c-552 active site with a conformation of the CXXCH loop that better mimics the protein crystal structure was generated (see Figure 1).

Perhaps the most important is the ability of the kinase domain to adopt a conformation that is compatible with the compound, as seems to be the case for the Takeda compounds because they interact with a conformation of GRK2 that has not yet been observed in other GRKs.

The A site for Mg2+ in our structure is more closely associated with the A conformation of E96 at a distance of 2.0 Å between the coordinating oxygen and Mg2+.

This behavior suggested that terminal amide linkages at 3′ and/or 5′ ends do not interfere with the typical A conformation of dsRNA.

Conversely, interaction of PAMs with mGluR5 could stabilize a conformation of the receptor that would facilitate activation of neuroprotective pathways, including Akt and ERK1/2, without triggering Gαq/11/InsP3/Ca2+ activation.

In this work, the lattice self-consistent field theory (SCFT) is modified to obtain the native state with a definite conformation of a given protein chain.

The solvent-induced crystallization of sPS yielded an ordered crystalline γ-form packed with a helical conformation of lower degrees of perfection.

Starting with a helical conformation of the gp120 fragment, backbone atoms and homologous side chain atoms were template forced onto the CCL4 structure during this protocol.

Molecular modeling suggests that recognition of the UAG/UAA and UGA in stop codons is associated with a different conformation of eRF1 (Fan-Minogue et al. 2008).

Correspondingly, in the ATP analog state, we observed density consistent with a docked conformation of the neck linker, extending towards the microtubule plus end, while in the no-nucleotide state the neck linker was evidently disordered, consistent with previous observations (Rice et al., 1999; Sindelar and Downing, 2007, 2010).