Sentence examples for with a common target from inspiring English sources

The finding of dose addition for the 11 tested pyrethroids is consistent with a common target site, the voltage-gated sodium channel (Narahashi 2000; Soderlund et al. 2002).

Resistance to drugs interacting with different cellular targets is likely associated with weaker pleiotropic constraints than to drugs with a common target.

The estimation of drug-drug relationships was thus restated in a classification framework that prioritizes drug pairs with a common target.

This drug/target activity view point led us to develop a new target-centric drug-drug relationship score (DRS) under the assumption that drugs that bind with a common target have other common factors.

The number of genes regulated by the same TF varies between 1 and 226 with a mean of 35.2, while the number of genes with a common target mRNA motif varies between 6 and 1138 with a mean of 81.7.

In our method, to represent drug pairs with their target information, the estimation of drug-drug relationships was restated as a large-scale classification problem that distinguished drug pairs with a common target.

Furthermore the best way to compare performance is controversial: is it the time with glucose within a common target range, the hyperglycaemia index, the recently described glycaemic penalty index [ 11], or the variability that would be associated with outcome [ 12]?

Alternatively, MUL1 could function in a parallel pathway to PINK1/Parkin, but with action on a common target such as Mfn.

RAL reduction of u-PA-dependent proliferation was similar to the inhibition caused by the antagonist antibodies (p < 0.001 in normal and RA synoviocytes) (Fig. 2b) and was not increased by co-treatment with them, indicating a common target for RAL and anti u-PA/u-PAR antibodies (data not shown).

Another frequent example happens when a user belongs to multiple groups with distinct permissions to a common target resource.

Patients with obesity are also a common target of derogatory humor by students, attendings and residents [ 8].