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A case-control study was performed with a case to control ratio of 1 4.
Controls were matched with cases by 5-year age group and study centre, with a case to control ratio of 1 : 2.
A total of 288 RV infection cases were required to compute a vaccine effectiveness of 70% with a statistical power of 80% using a matched design with a case to control ratio of 1 4.
(5) The use of a mixed ANOVA design to compare a case to controls (with or without the adjustment proposed by Corballis) is beset with problems but these can be overcome using alternative methods.
The control populations were selected randomly within each study to represent the patient population at risk for lung cancer that would be candidates for CT screening, with a ratio of case to control of 1 to 3.5.
Generally speaking, case control studies compare cases with an event to controls without the event, looking for differences in the antecedent exposures [ 10].
We estimated that at 80% power and 5% level of significance, with a ratio of cases to controls of 1∶1, a matched sample size of 132 cases and 132 controls could detect an odds ratio of 2.2.
The number of control subjects was lower than the overall number of case subjects, thus reducing the power of analyses; comparisons between control and case subjects with single complications allowed a more favorable case-to-control ratio, but multiple comparisons within the same case-control study base might have caused significant results due to chance.
MDR creates a classification rule based on these combinations using a Naïve Bayes classifier, assigning genotype combinations with a large ratio of cases to controls as high-risk and low-risk otherwise [ 6].
For each SNP in the sequence, we created several artificial case-control studies each with a 1 1 ratio of cases to controls.
8, a matched case control design with clinical site matching cases to controls was used.
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